PPARA anticorps (N-Term)
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- Antigène Voir toutes PPARA Anticorps
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Chévre, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PPARA est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EISQSIGEDS SGSFGFTEYQ YLGSCPGSDG SVITDTLSPA SSPSSVTYPV
- Homologie
- Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PPARA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the n terminal region of human PPARA
- Top Product
- Discover our top product PPARA Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 468 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
- Autre désignation
- PPARA (PPARA Produits)
- Synonymes
- anticorps NR1C1, anticorps PPAR, anticorps PPARalpha, anticorps hPPAR, anticorps LOC100136415, anticorps PPARALPHA, anticorps nr1c1, anticorps xPPARalpha, anticorps xppara, anticorps 4933429D07Rik, anticorps AW742785, anticorps Nr1c1, anticorps PPAR-alpha, anticorps Ppar, anticorps peroxisome proliferator activated receptor alpha, anticorps peroxisome proliferator-activated receptor alpha, anticorps peroxisome proliferator activated receptor alpha L homeolog, anticorps PPARA, anticorps LOC100136415, anticorps ppara.L, anticorps Ppara, anticorps ppara
- Sujet
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Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. PPARA is the subtype PPAR-alpha, which is a nuclear transcription factor.Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
Alias Symbols: MGC2237, MGC2452, NR1C1, PPAR, hPPAR, PPARalpha
Protein Interaction Partner: SIRT1, PRMT1, PRMT8, RXRA, CHD9, NCOA1, FOXA3, CDK3, TNP1, HSP90AA1, NCOR2, NCOR1, SUMO1, UBE2I, LPIN1, SRC, TRA, MECR, STAC3, HELZ2, NRBF2, AIP, NR1H3, MED24, GADD45G, GADD45B, AKAP13, PPARGC1A, MED1, EP300, NRIP1, DAP3, MAPK3, DUT, RXRG, PRKCD, PRKCA, M
Protein Size: 468 - Poids moléculaire
- 52 kDa
- ID gène
- 5465
- NCBI Accession
- NM_005036, NP_005027
- UniProt
- Q07869
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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