PRKAR2A anticorps (Middle Region)
-
- Antigène Voir toutes PRKAR2A Anticorps
- PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))
-
Épitope
- Middle Region
- Reactivité
- Humain, Rat, Souris, Porc, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PRKAR2A est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- DILVTKDNQT RSVGQYDNRG SFGELALMYN TPRAATIVAT SEGSLWGLDR
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PRKAR2A. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PRKAR2A Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 404 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))
- Autre désignation
- PRKAR2A (PRKAR2A Produits)
- Synonymes
- anticorps PKR2, anticorps PRKAR2, anticorps prkar2a, anticorps zgc:85886, anticorps PRKAR2A, anticorps 1110061A24Rik, anticorps AI317181, anticorps AI836829, anticorps RII(alpha), anticorps protein kinase cAMP-dependent type II regulatory subunit alpha, anticorps protein kinase, cAMP-dependent, regulatory, type II, alpha, B, anticorps protein kinase, cAMP-dependent, regulatory, type II, alpha, anticorps protein kinase, cAMP dependent regulatory, type II alpha, anticorps protein kinase cAMP-dependent type 2 regulatory subunit alpha, anticorps PRKAR2A, anticorps prkar2ab, anticorps Prkar2a
- Sujet
-
CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).
Alias Symbols: MGC3606, PKR2, PRKAR2
Protein Interaction Partner: UBC, SUZ12, IMPDH2, GPS1, CSRP1, KPNA6, PRKACB, PRKACA, GCH1, WASF1, VCP, CIRBP, ELAVL1, PJA2, Dynll1, AKAP7, PPP1CB, MYCBPAP, ARFGEF2, AKAP2, RAB32, NBEA, AKAP12, AKAP11, AKAP10, AKAP8, AKAP6, AKAP3, AKAP5, AKAP13, AKAP9, CBFA2T3, SMAD3, AKAP1, CFTR, SMA
Protein Size: 404 - Poids moléculaire
- 44 kDa
- ID gène
- 5576
- NCBI Accession
- NM_004157, NP_004148
- UniProt
- P13861
- Pathways
- Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
-