PRKAR2A anticorps (pSer99)

N° du produit ABIN7269661

Détail du produit anti-PRKAR2A anticorps

Antigène: PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))

Épitope: pSer99

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PRKAR2A est non-conjugé

Application: Western Blotting (WB)

Fonction: Phospho-PKA RIIα (PRKAR2A)-S99 Rabbit mAb

Réactivité croisée: Humain, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding S99 of human PRKAR2A/PKR2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRKAR2A

Antigène: PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))

Autre désignation: PRKAR2A (PRKAR2A Produits)

Synonymes: anticorps PKR2, anticorps PRKAR2, anticorps prkar2a, anticorps zgc:85886, anticorps PRKAR2A, anticorps 1110061A24Rik, anticorps AI317181, anticorps AI836829, anticorps RII(alpha), anticorps protein kinase cAMP-dependent type II regulatory subunit alpha, anticorps protein kinase, cAMP-dependent, regulatory, type II, alpha, B, anticorps protein kinase, cAMP-dependent, regulatory, type II, alpha, anticorps protein kinase, cAMP dependent regulatory, type II alpha, anticorps protein kinase cAMP-dependent type 2 regulatory subunit alpha, anticorps PRKAR2A, anticorps prkar2ab, anticorps Prkar2a

Sujet: CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 2008],PKR2, PRKAR2,Apoptosis,Apoptosis_Inhibition of Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cancer,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Endocrine & Metabolism,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Insulin Receptor Signaling Pathway,Kinase,MAPK-Erk Signaling Pathway,Neurodegenerative Diseases,Neurodegenerative Diseases_Dopamine Signaling in Parkinsons Disease,Neuroscience,Signal Transduction,PRKAR2A

Poids moléculaire: 51kDa

ID gène: 5576

UniProt: P13861

Pathways: Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2