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CDC42 anticorps (AA 25-191)
CDC42
Reactivité: Humain
WB, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN3021671
Détail du produit anti-CDC42 anticorps
(cache)
Antigène
Voir toutes CDC42 Anticorps
CDC42
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
Épitope
Tous les épitopes à travers CDC42 Anticorps.
AA 25-191
Reactivité
Toutes les réactivités sur CDC42 Anticorps
Humain
Hôte
Toutes les hôtes sur CDC42 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CDC42 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CDC42 Anticorps
Cet anticorp CDC42 est non-conjugé
Application
Tous les applications à travers CDC42 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Séquence
TNKFPSEYVP TVFDNYAVTV MIGGEPYTLG LFDTAGQEDY DRLRPLSYPQ TDVFLVCFSV VSPSSFENVK EKWVPEITHH CPKTPFLLVG TQIDLRDDPS TIEKLAKNKQ KPITPETAEK LARDLKAVKY VECSALTQKG LKNVFDEAIL AALEPPEPKK SRRCVLL
Réactivité croisée
Humain, Souris, Rat
Attributs du produit
Polyclonal Antibodies
Purification
Affinity purification
Immunogène
Recombinant fusion protein containing a sequence corresponding to amino acids 25-191 of human CDC42 (NP_001782.1).
Isotype
IgG
Alternatives
(show)
Information d'application
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Indications d'application
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid freeze / thaw cycles
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Références pour anticorps anti-CDC42 (ABIN3021671)
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Liu, Feng, Chen, Luo, Yan, Chen, Lin, Ding, Wen : "Dcf1 Triggers Dendritic Spine Formation and Facilitates Memory Acquisition. " dans: Molecular neurobiology , Vol. 55 , Issue 1 , pp. 763-775 , (2018 ) (PubMed ).
Fang, Li, Han, Zhao, Gao, Yan, Luo : "Overexpression cdc42 attenuates isoflurane-induced neurotoxicity in developmental brain of rats. " dans: Biochemical and biophysical research communications , Vol. 490 , Issue 3 , pp. 719-725 , (2017 ) (PubMed ).
Détails sur CDC42
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Antigène
CDC42
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
Autre désignation
CDC42 (CDC42 Produits )
Synonymes
anticorps CDC42Hs, anticorps G25K, anticorps AI747189, anticorps AU018915, anticorps cdc42a, anticorps wu:fb07d08, anticorps wu:fj62g06, anticorps zgc:63918, anticorps Xcdc42, anticorps cdc42hs, anticorps g25k, anticorps CDC42, anticorps CG12530, anticorps Cdc42Dm, anticorps D-CDC42, anticorps D-Cdc42, anticorps D-cdc42, anticorps DCDC42, anticorps DCdc42, anticorps Dcdc42, anticorps Dm Cdc42, anticorps DmCDC42, anticorps Dmcdc42, anticorps Dmel\\CG12530, anticorps cdc42, anticorps cell division cycle 42, anticorps Cell division control protein 42 homolog, anticorps cell division control protein 42 homolog, anticorps cell division cycle 42 L homeolog, anticorps CG12530 gene product from transcript CG12530-RC, anticorps Rho family GTPase, anticorps CDC42, anticorps Cdc42, anticorps cdc42, anticorps LOC100636735, anticorps LOC100637699, anticorps LOC100638834, anticorps cdc42.L
Sujet
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.,CDC42,CDC42Hs,G25K,TKS,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Kinase,ErbB-HER Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell Adhesion,Cytoskeleton,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,Cytokines,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,CDC42
Poids moléculaire
21 kDa
ID gène
998
UniProt
P60953
Pathways
Signalisation MAPK , Dynamique des Microtubules , Signalisation RTK , Signalisation WNT , TCR Signaling , EGFR Signaling Pathway , Regulation of Actin Filament Polymerization , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Maintenance of Protein Location , Skeletal Muscle Fiber Development , Signaling Events mediated by VEGFR1 and VEGFR2 , EGFR Downregulation , VEGF Signaling
Vus récemment
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