BCL10 anticorps (AA 1-233)

N° du produit ABIN3042330

Détail du produit anti-BCL10 anticorps

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Épitope: AA 1-233

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL10 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for B-cell lymphoma/leukemia 10(BCL10) detection. Tested with WB in Human,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for B-cell lymphoma/leukemia 10(BCL10) detection. Tested with WB in Human,Rat.
Gene Name: B-cell CLL/lymphoma 10
Protein Name: B-cell lymphoma/leukemia 10

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Bcl10 recombinant protein (Position: M1-Q233). Human Bcl10 shares 91% and 91.4% amino acid (aa) sequence identity with mouse and rat Bcl10, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur BCL10

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Autre désignation: BCL10 (BCL10 Produits)

Synonymes: anticorps CARMEN, anticorps CIPER, anticorps CLAP, anticorps c-E10, anticorps mE10, anticorps BCL10, anticorps AI132454, anticorps BCL-10, anticorps C81403, anticorps ME10, anticorps cE10, anticorps bcl10, anticorps B-cell CLL/lymphoma 10, anticorps B-cell lymphoma/leukemia 10-like, anticorps B cell leukemia/lymphoma 10, anticorps B-cell lymphoma/leukemia 10, anticorps BCL10, anticorps Bcl10, anticorps bcl10, anticorps LOC100223183

Sujet: BCL10, B-cell CLL/lymphoma 10, gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The BCL10 gene is mapped to chromosome 1p22. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. And this protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.

Synonyms: AI132454 antibody|B cell CLL/lymphoma 10 antibody|B cell lymphoma/leukemia10 antibody|B-cell CLL/lymphoma 10 antibody|B-cell leukemia/lymphoma 10 antibody|B-cell lymphoma/leukemia 10 antibody|Bcl 10 antibody|Bcl-10 antibody|Bcl10 antibody|BCL10_HUMAN antibody|c E10 antibody|c-E10 antibody|C81403 antibody|CARD containing apoptotic signaling protein antibody|CARD containing molecule enhancing NF kappa B antibody|CARD containing molecule enhancing NF kB antibody|CARD containing molecule enhancing NF-kB antibody|CARD containing molecule enhancing NFkB antibody|CARD containing proapoptotic protein antibody|CARD like apoptotic protein antibody|CARD-containing apoptotic signaling protein antibody|CARD-containing molecule enhancing NF-kappa-B antibody|CARD-containing proapoptotic protein antibody|CARD-like apoptotic protein antibody|CARMEN antibody|Caspase recruiting domain containing protein antibody|caspase-recruiting domain-containing protein antibody|cCARMEN antibody|cE 10 antibody|cE10 antibody|CED 3/ICH 1 prodomain homologous E10 like regulator antibody|CED-3/ICH-1 prodomain homologous E10-like regulator antibody|CED3/ICH1 prodomain homologous E10 like regulator antibody|Cellular E10 antibody|Cellular homolog of vCARMEN antibody|Cellular-E10 antibody|CIPER antibody|CLAP antibody|hCLAP antibody|Mammalian CARD containing adapter molecule E10 antibody|Mammalian CARD-containing adapter molecule E10 antibody|mE 10 antibody|mE10 antibody|R-RCD1 antibody

ID gène: 8915

UniProt: O95999

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins