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GRB2 anticorps (AA 187-216)
GRB2
Reactivité: Humain
WB, IHC (p)
Hôte: Lapin
Polyclonal
RB11305-11306
unconjugated
Détail du produit anti-GRB2 anticorps
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Antigène
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GRB2
(Growth Factor Receptor-Bound Protein 2 (GRB2))
Épitope
Tous les épitopes à travers GRB2 Anticorps.
AA 187-216
Reactivité
Toutes les réactivités sur GRB2 Anticorps
Humain
Hôte
Toutes les hôtes sur GRB2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur GRB2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers GRB2 Anticorps
Cet anticorp GRB2 est non-conjugé
Application
Tous les applications à travers GRB2 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
X, C, M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
Clone
RB11305-11306
Isotype
Ig Fraction
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Information d'application
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Indications d'application
WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Références pour anticorps anti-GRB2 (ABIN390236)
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Gogate, Kurenova, Ethirajan, Liao, Yemma, Sen, Pandey, Cance : "Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer. " dans: Cancer letters , Vol. 353 , Issue 2 , pp. 281-9 , (2014 ) (PubMed ).
Détails sur GRB2
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Antigène
GRB2
(Growth Factor Receptor-Bound Protein 2 (GRB2))
Autre désignation
GRB2 (GRB2 Produits )
Synonymes
anticorps GRB2, anticorps grb2, anticorps AA408164, anticorps Ash, anticorps ASH, anticorps EGFRBP-GRB2, anticorps Grb3-3, anticorps MST084, anticorps MSTP084, anticorps NCKAP2, anticorps wu:fb18e12, anticorps wu:fb34e06, anticorps zgc:73077, anticorps growth factor receptor bound protein 2, anticorps growth factor receptor-bound protein 2, anticorps growth factor receptor-bound protein 2b, anticorps GRB2, anticorps grb2, anticorps Grb2, anticorps grb2b
Sujet
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
Poids moléculaire
25206
ID gène
2885
NCBI Accession
NP_002077 , NP_987102
UniProt
P62993
Pathways
Signalisation RTK , TCR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Actin Filament Polymerization , Hepatitis C , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , EGFR Downregulation
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