Caspase 9 anticorps
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- Antigène Voir toutes Caspase 9 (CASP9) Anticorps
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Caspase 9 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family (1,2). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Another cleavage occurs at Asp330 producing a p37 subunit that can serve to amplify the apoptotic response (3-6). Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to initiate a caspase cascade, which leads to apoptosis (7-10).
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human CASP9.
- Isotype
- IgG
- Top Product
- Discover our top product CASP9 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 , IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C.
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- Antigène
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- Autre désignation
- CASP9 (CASP9 Produits)
- Synonymes
- anticorps CASP9, anticorps AI115399, anticorps APAF-3, anticorps AW493809, anticorps CASP-9, anticorps Caspase-9, anticorps ICE-LAP6, anticorps Mch6, anticorps Apaf3, anticorps Casp-9-CTD, anticorps Casp9_v1, anticorps Ice-Lap6, anticorps APAF3, anticorps MCH6, anticorps PPP1R56, anticorps caspase 9, anticorps CASP9, anticorps Casp9
- ID gène
- 842
- UniProt
- P55211
- Pathways
- Signalisation MAPK, Signalisation RTK, Apoptose, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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