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PDGFRA anticorps
PDGFRA
Reactivité: Humain, Souris, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-PDGFRA anticorps
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Antigène
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PDGFRA
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
Reactivité
Toutes les réactivités sur PDGFRA Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur PDGFRA Anticorps
Lapin
Clonalité
Toutes les clonalités sur PDGFRA Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PDGFRA Anticorps
Cet anticorp PDGFRA est non-conjugé
Application
Tous les applications à travers PDGFRA Anticorps.
Western Blotting (WB)
Specificité
This antibody detects endogenous levels of PDGFR-alpha protein. (region surrounding Ile843)
Réactivité croisée (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography
Pureté
> 95 % by SDS-PAGE
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Information d'application
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Indications d'application
Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur PDGFRA
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Antigène
PDGFRA
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
Autre désignation
CD140a / PDGFRA (PDGFRA Produits )
Synonymes
anticorps AI115593, anticorps CD140a, anticorps Pdgfr-2, anticorps APDGFR, anticorps PDGFACE, anticorps CD140A, anticorps PDGFR-2, anticorps PDGFR2, anticorps RHEPDGFRA, anticorps PDGFR, anticorps PDGFR-A, anticorps platelet derived growth factor receptor alpha, anticorps platelet derived growth factor receptor, alpha polypeptide, anticorps platelet-derived growth factor receptor, alpha polypeptide L homeolog, anticorps platelet-derived growth factor receptor, alpha polypeptide, anticorps PDGFRA, anticorps Pdgfra, anticorps pdgfra.L
Sujet
Platelet-derived growth factor receptors exhibit tyrosineprotein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGFalpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
Poids moléculaire
approx. 140, 190 kDa
ID gène
5156
NCBI Accession
NP_006197
UniProt
P16234
Pathways
Signalisation RTK , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Platelet-derived growth Factor Receptor Signaling
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