NEDD9 anticorps (AA 82-398)

N° du produit ABIN534196

Détail du produit anti-NEDD9 anticorps

Antigène: NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Épitope: AA 82-398

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NEDD9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Fonction: Mouse monoclonal antibody raised against partial recombinant NEDD9.

Specificité: Human, mouse, rat NEDD9. Does not recognize p130Cas. Have not tested on Sin1. This mAb mostly detects HEF1 localized at the focal adhesion sites.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Purification: Purified

Immunogène: Recombinant GST fusion protein corresponding to amino acids 82-398 of human NEDD9.

Clone: 2G9

Isotype: IgG1

Information d'application

Indications d'application: Western Blot (1:1000)
Immunoprecipitation (1:2000-1:6000)
Immunofluorescence (1:500)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-NEDD9 (ABIN534196)

Liu, Wang, Zhao, Zhu, Yin, Wei, Wu, Cheng, Wang, Ni, Wang, Cao, Huang, Cai: "NEDD9 overexpression correlates with poor prognosis in gastric cancer." dans: Tumour biology, Vol. 35, Issue 7, pp. 6351-6, (2014) (PubMed).

Regelmann, Danzl, Wanjalla, Alexandropoulos: "The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking." dans: Immunity, Vol. 25, Issue 6, pp. 907-18, (2006) (PubMed).

Bargon, Gunning, ONeill: "The Cas family docking protein, HEF1, promotes the formation of neurite-like membrane extensions." dans: Biochimica et biophysica acta, Vol. 1746, Issue 2, pp. 143-54, (2005) (PubMed).

ONeill, Golemis: "Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics." dans: Molecular and cellular biology, Vol. 21, Issue 15, pp. 5094-108, (2001) (PubMed).

Détails sur NEDD9

Antigène: NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Autre désignation: NEDD9 (NEDD9 Produits)

Synonymes: anticorps NEDD9, anticorps CAS-L, anticorps CAS2, anticorps CASL, anticorps CASS2, anticorps HEF1, anticorps Cas-L, anticorps CasL, anticorps E230025G09Rik, anticorps neural precursor cell expressed, developmentally down-regulated 9, anticorps neural precursor cell expressed, developmentally down-regulated gene 9, anticorps NEDD9, anticorps Nedd9

ID gène: 4739