BRAF anticorps (pThr598)

N° du produit ABIN548622

Détail du produit anti-BRAF anticorps

Antigène: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Épitope: pThr598

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRAF est non-conjugé

Application: ELISA, Dot Blot (DB)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRAF.

Réactivité croisée: Humain

Immunogène: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T598 of human BRAF.

Information d'application

Indications d'application: ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-BRAF (ABIN548622)

Yamaguchi, Wallace, Magenheimer, Hempson, Grantham, Calvet: "Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype." dans: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40419-30, (2004) (PubMed).

Frattini, Ferrario, Bressan, Balestra, De Cecco, Mondellini, Bongarzone, Collini, Gariboldi, Pilotti, Pierotti, Greco: "Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer." dans: Oncogene, Vol. 23, Issue 44, pp. 7436-40, (2004) (PubMed).

Loewe, Kittler, Fischer, Faé, Wolff, Petzelbauer: "BRAF kinase gene V599E mutation in growing melanocytic lesions." dans: The Journal of investigative dermatology, Vol. 123, Issue 4, pp. 733-6, (2004) (PubMed).

Détails sur BRAF

Antigène: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Autre désignation: B-Raf proto-oncogene (BRAF Produits)

Synonymes: anticorps B-RAF1, anticorps BRAF1, anticorps NS7, anticorps RAFB1, anticorps C-RMIL, anticorps RMIL, anticorps B-Raf, anticorps braf1, anticorps rafb1, anticorps b-raf1, anticorps sierrabraf, anticorps BRAF, anticorps 9930012E13Rik, anticorps AA120551, anticorps AA387315, anticorps AA473386, anticorps B-raf, anticorps Braf-2, anticorps Braf2, anticorps C230098H17, anticorps C87398, anticorps D6Ertd631e, anticorps braf, anticorps fc48g01, anticorps wu:fc48g01, anticorps B-Raf proto-oncogene, serine/threonine kinase, anticorps B-Raf proto-oncogene, serine/threonine kinase S homeolog, anticorps Braf transforming gene, anticorps si:dkey-222f8.3, anticorps BRAF, anticorps Braf, anticorps braf.S, anticorps braf, anticorps si:dkey-222f8.3

ID gène: 673

Pathways: Signalisation MAPK, Signalisation RTK, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy