IL-1 beta anticorps (AA 148-174)
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- Antigène Voir toutes IL-1 beta (IL1B) Anticorps
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Épitope
- AA 148-174
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-1 beta est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This IL1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IL1B Anticorps primaire
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- Indications d'application
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For FACS starting dilution is: 1:25
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Autre désignation
- IL1B (IL1B Produits)
- Synonymes
- anticorps IL-1, anticorps IL1-BETA, anticorps IL1F2, anticorps IL-1BETA, anticorps IL1beta, anticorps il1-b, anticorps zgc:111873, anticorps IL-1B, anticorps IL-1beta, anticorps Il-1b, anticorps IL1B, anticorps IL-1 beta, anticorps IL-1b, anticorps interleukin 1 beta, anticorps interleukin 1, beta, anticorps IL1B, anticorps il1b, anticorps Il1b
- Sujet
- IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (,CNS), is found to contribute to inflammatory pain hypersensitivity.
- Poids moléculaire
- 31 kDa
- ID gène
- 3553
- UniProt
- P01584
- Pathways
- Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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