GFR anticorps (C-Term)

N° du produit ABIN5535165

Détail du produit anti-GFR anticorps

Antigène: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Épitope: AA 529-555, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFR est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RAPGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-555 amino acids from the C-terminal region of human RAPGEF5.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GFR

Antigène: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Autre désignation: RAPGEF5 (RAPGEF5 Produits)

Synonymes: anticorps GFR, anticorps MR-GEF, anticorps REPAC, anticorps 4932413M22, anticorps C86120, anticorps D030051B22Rik, anticorps Mrgef, anticorps mKIAA0277, anticorps mmr-gef, anticorps RGD1562891, anticorps rMR-GEF, anticorps MGC154311, anticorps Rap guanine nucleotide exchange factor 5, anticorps Rap guanine nucleotide exchange factor (GEF) 5, anticorps Rap guanine nucleotide exchange factor 5 S homeolog, anticorps RAPGEF5, anticorps Rapgef5, anticorps rapgef5.S

Sujet: Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).

Poids moléculaire: 68 kDa

ID gène: 9771

UniProt: Q92565

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, Hepatitis C