CENPF anticorps

N° du produit ABIN5697310

Détail du produit anti-CENPF anticorps

Antigène: CENPF (Centromere Protein F (CENPF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPF est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogène: centromere protein F, 350/400ka (mitosin)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur CENPF

Antigène: CENPF (Centromere Protein F (CENPF))

Autre désignation: CENPF (CENPF Produits)

Synonymes: anticorps LOC100222985, anticorps 6530404A22Rik, anticorps AI325968, anticorps CENF, anticorps Lek1, anticorps PRO1779, anticorps mitosin, anticorps im:7140452, anticorps im:7144238, anticorps im:7154719, anticorps im:7156761, anticorps si:ch211-152h14.2, anticorps hcp-1, anticorps CMF1, anticorps centromere protein F, anticorps CENPF, anticorps Cenpf, anticorps cenpf

Sujet: Synonyms: Background:Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia.

ID gène: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2