Retinoblastoma Binding Protein 8 anticorps

N° du produit ABIN5697461

Détail du produit anti-Retinoblastoma Binding Protein 8 anticorps

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé

Application: ELISA, Western Blotting (WB)

Immunogène: retinoblastoma binding protein 8

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur Retinoblastoma Binding Protein 8

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Autre désignation: RBBP8 (RBBP8 Produits)

Synonymes: anticorps COM1, anticorps CTIP, anticorps JWDS, anticorps RIM, anticorps SAE2, anticorps SCKL2, anticorps 9930104E21Rik, anticorps CtIP, anticorps RBBP-8, anticorps RGD1308872, anticorps RBBP8, anticorps DKFZp469K0714, anticorps RB binding protein 8, endonuclease, anticorps retinoblastoma binding protein 8, endonuclease, anticorps retinoblastoma binding protein 8 L homeolog, anticorps retinoblastoma binding protein 8, anticorps RBBP8, anticorps Rbbp8, anticorps rbbp8.L, anticorps rbbp8

Sujet: Synonyms:CTIP Background:Endonuclease that cooperates with the MRE11-RAD50-NBN(MRN) complex in processing meiotic and mitotic double-strand breaks(DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining(A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.

ID gène: 5932

UniProt: Q99708

Pathways: Cycle Cellulaire, Réparation de l'ADN