CCDC98 anticorps
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- Antigène Voir toutes CCDC98 (FAM175A) Anticorps
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CCDC98 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Immunogène
- family with sequence similarity 175, member A
- Isotype
- IgG
- Top Product
- Discover our top product FAM175A Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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human testis tissue were subjected to SDS PAGE followed by western blot with FNab02974(FAM175A antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
- Autre désignation
- FAM175A (FAM175A Produits)
- Synonymes
- anticorps CCDC98, anticorps abra1, anticorps ccdc98, anticorps fam175a, anticorps ABRA1, anticorps 3830405G04Rik, anticorps 5630400M01Rik, anticorps AI506069, anticorps AL024423, anticorps AV118690, anticorps Ccdc98, anticorps RGD1305287, anticorps zgc:103522, anticorps abraxas 1, BRCA1 A complex subunit, anticorps Coiled-coil domain-containing protein 98, anticorps BRCA1 A complex subunit, anticorps family with sequence similarity 175 member A, anticorps abraxas 2a, BRISC complex subunit, anticorps abraxas 1, BRCA1 A complex subunit S homeolog, anticorps ABRAXAS1, anticorps abraxas1, anticorps Abraxas1, anticorps FAM175A, anticorps abraxas2a, anticorps abraxas1.S
- Sujet
- Synonyms:ABRA1, CCDC98 Background:Involved in DNA damage response and double-strand break(DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
- Poids moléculaire
- 46 kDa
- ID gène
- 84142
- UniProt
- Q6UWZ7
- Pathways
- Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
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