DYNLT1 anticorps

N° du produit ABIN5708410

Détail du produit anti-DYNLT1 anticorps

Antigène: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DYNLT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: A recombinant human partial protein corresponding to amino acids M1-A80 was used as the immunogen for the DYNLT1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DYNLT1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the DYNLT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur DYNLT1

Antigène: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Autre désignation: DYNLT1 (DYNLT1 Produits)

Synonymes: anticorps cw-1, anticorps tctel1, anticorps dynlt1a, anticorps tctex-1, anticorps MGC85297, anticorps tctex1, anticorps Ci-LC3, anticorps CW-1, anticorps TCTEL1, anticorps AGS2, anticorps Tctex1, anticorps dynein light chain Tctex-type 1 L homeolog, anticorps dynein light chain Tctex-type 1, anticorps dynein, light chain, Tctex-type 1, anticorps dynlt1.L, anticorps DYNLT1, anticorps dynlt1, anticorps Dynlt1

Sujet: Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene. This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P63172

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling