PHLPP1 anticorps (AA 1508-1717)
-
- Antigène Voir toutes PHLPP1 Anticorps
- PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))
-
Épitope
- AA 1508-1717
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PHLPP1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Séquence
- PAYPSEQRCM LHPICLSNSF QRQLSSATFS SAFSDNGLDS DDEEPIEGVF TNGSRVEVEV DIHCSRAKEK EKQQHLLQVP AEASDEGIVI SANEDEPGLP RKADFSAVGT IGRRRANGSV APQERSHNVI EVATDAPLRK PGGYFAAPAQ PDPDDQFIIP PELEEEVKEI MKHHQEQQQQ QQPPPPPQLQ PQLPRHYQLD QLPDYYDTPL
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1508-1717 of human PHLPP1 (NP_919431.2).
- Isotype
- IgG
-
-
- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Commentaires
-
HIGH QUALITY
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))
- Autre désignation
- PHLPP1 (PHLPP1 Produits)
- Synonymes
- anticorps PHLPP, anticorps PLEKHE1, anticorps SCOP, anticorps AI836256, anticorps Phlpp, anticorps Plekhe1, anticorps mKIAA0606, anticorps Scop, anticorps PH domain and leucine rich repeat protein phosphatase 1, anticorps PHLPP1, anticorps phlpp1, anticorps Phlpp1
- Sujet
- This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.,PHLPP1,PHLPP,PLEKHE1,PPM3A,SCOP,Cancer,Tumor suppressors,Invasion and Metastasis,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Phosphatase of Akt,PHLPP1
- Poids moléculaire
- 133 kDa/184 kDa
- ID gène
- 23239
- UniProt
- O60346
- Pathways
- Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
-