CYP1A2 anticorps (Internal Region)

N° du produit ABIN6258052

Détail du produit anti-CYP1A2 anticorps

Antigène: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP1A2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Cytochrome P450 1A2 Antibody detects endogenous levels of total Cytochrome P450 1A2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Cytochrome P450 1A2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CYP1A2

Antigène: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Autre désignation: CYP1A2 (CYP1A2 Produits)

Synonymes: anticorps CP12, anticorps P3-450, anticorps P450(PA), anticorps CYP1A2, anticorps CYPIA2, anticorps P450-PM4, anticorps Cyp1a1, anticorps P450-3, anticorps CYPD45, anticorps P-450d, anticorps RATCYPD45, anticorps CYP1A5, anticorps CP450, anticorps CYP-IA2, anticorps cytochrome P450 family 1 subfamily A member 2, anticorps cytochrome P450 1A2, anticorps cytochrome P450 LM4, anticorps cytochrome P450, family 1, subfamily A, polypeptide 2, anticorps cytochrome P450, family 1, subfamily a, polypeptide 2, anticorps cytochrome P450 1A2-like, anticorps CYP1A2, anticorps LOC100328937, anticorps Cyp1a2, anticorps VDBG_06455, anticorps LOC101825565, anticorps LOC102130662

Sujet:

Description: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

Gene: CYP1A2

Poids moléculaire: 55 kDa

ID gène: 1544

UniProt: P05177