SPHK1 anticorps

N° du produit ABIN6290942

Détail du produit anti-SPHK1 anticorps

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPHK1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant protein of human SPHK1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000
IF 1:50 - 1:200

Commentaires:

Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur SPHK1

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Autre désignation: SPHK1 (SPHK1 Produits)

Synonymes: anticorps CG1747, anticorps Dmel\\CG1747, anticorps SK1, anticorps Sphk1, anticorps SPHK1, anticorps F18E5.160, anticorps F18E5_160, anticorps sphingosine kinase 1, anticorps SPHK, anticorps 1110006G24Rik, anticorps Sk1, anticorps Spk1, anticorps Sphingosine kinase 1, anticorps sphingosine kinase 1, anticorps sphingosine kinase 1 L homeolog, anticorps Sk1, anticorps SPHK1, anticorps sphk1.L, anticorps Sphk1

Sujet: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 42.518 kDa

ID gène: 8877

UniProt: Q9NYA1

Pathways: VEGF Signaling