DIABLO anticorps
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- Antigène Voir toutes DIABLO Anticorps
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DIABLO est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human DIABLO (NP_063940.1).
- Isotype
- IgG
- Top Product
- Discover our top product DIABLO Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- Autre désignation
- DIABLO (DIABLO Produits)
- Synonymes
- anticorps smac, anticorps smac3, anticorps diablo-s, anticorps 0610041G12Rik, anticorps 1700006L01Rik, anticorps AU040403, anticorps Smac, anticorps DFNA64, anticorps SMAC, anticorps DBO, anticorps XSmac, anticorps diablo, IAP-binding mitochondrial protein, anticorps diablo IAP-binding mitochondrial protein, anticorps diablo, IAP-binding mitochondrial protein L homeolog, anticorps diablo, anticorps Diablo, anticorps DIABLO, anticorps diablo.L
- Sujet
- This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Poids moléculaire
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Observed_MW: 18kDa
Calculated_MW: 21kDa/22kDa/27kDa
- ID gène
- 56616
- UniProt
- Q9NR28
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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