NCOR2 anticorps

N° du produit ABIN6571720

Détail du produit anti-NCOR2 anticorps

Antigène: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOR2 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human NCOR2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NCOR2

Antigène: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Autre désignation: NCOR2 (NCOR2 Produits)

Synonymes: anticorps CTG26, anticorps N-CoR2, anticorps SMAP270, anticorps SMRT, anticorps SMRTE, anticorps SMRTE-tau, anticorps TNRC14, anticorps TRAC, anticorps TRAC-1, anticorps TRAC1, anticorps N-CoR, anticorps SMRTe, anticorps NCOR2, anticorps gb:be017685, anticorps si:bz71m17.2, anticorps smrt, anticorps ctg26, anticorps smrte, anticorps trac1, anticorps tnrc14, anticorps trac-1, anticorps smrte-tau, anticorps nuclear receptor corepressor 2, anticorps nuclear receptor co-repressor 2, anticorps NCOR2, anticorps Ncor2, anticorps ncor2

Sujet:

Synonyms: CTG 26,CTG repeat protein 26,CTG26,N CoR2,N-CoR2,NCoR 2,Ncor2,NCOR2,Nuclear Receptor Co-Repressor 2,Nuclear receptor corepressor 2,retinoic-acid-receptor-associated corepressor,Silencing Mediator for Retanoid and Thyroid Hormone Receptors,Silencing mediator of retinoic acid and thyroid hormone receptor,SMAP 270,SMAP270,SMRT,SMRTE,SMRTE tau,T3 receptor associating factor,T3 receptor-associating factor,Thyroid retinoic acid receptor associated corepressor,Thyroid-,TNRC 14,TNRC14,TRAC 1,TRAC,TRAC1

Background: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire:

Observed_MW: 180kDa

Calculated_MW: 81kDa/268kDa/273kDa/274kDa

ID gène: 9612

UniProt: Q9Y618

Pathways: Signalisation Notch, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha