MDM2 anticorps (C-Term)

N° du produit ABIN6923101

Détail du produit anti-MDM2 anticorps

Antigène: MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of MDM2.

Réactivité croisée: Humain, Souris

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MDM2.

Information d'application

Indications d'application: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-MDM2 (ABIN6923101)

Mantesso, Loducca, Bendit, Garicochea, Nunes, de Araújo: "Mdm2 mRNA expression in salivary gland tumour cell lines." dans: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 33, Issue 2, pp. 96-101, (2004) (PubMed).

Schon, Friedler, Freund, Fersht: "Binding of p53-derived ligands to MDM2 induces a variety of long range conformational changes." dans: Journal of molecular biology, Vol. 336, Issue 1, pp. 197-202, (2004) (PubMed).

Burch, Scott, Pohler, Meek, Hupp: "Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1." dans: Journal of molecular biology, Vol. 337, Issue 1, pp. 115-28, (2004) (PubMed).

Détails sur MDM2

Antigène: MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Autre désignation: MDM2 (MDM2 Produits)

Synonymes: anticorps ACTFS, anticorps HDMX, anticorps hdm2, anticorps zgc:109834, anticorps 1700007J15Rik, anticorps AA415488, anticorps Mdm-2, anticorps MDM2 proto-oncogene, anticorps MDM2 proto-oncogene S homeolog, anticorps Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse), anticorps MDM2 oncogene, E3 ubiquitin protein ligase, anticorps transformed mouse 3T3 cell double minute 2, anticorps MDM2, anticorps mdm2.S, anticorps Mdm2, anticorps mdm2

ID gène: 4193

Pathways: Signalisation p53, Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway