CD11c anticorps

N° du produit ABIN6937591

Détail du produit anti-CD11c anticorps

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11c est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Specificité: CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst, expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human monocytic U937 phorbol ester-treated cells

Clone: HC1-1

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Functional Studies (Order Ab without BSA & Azide), Optimal dilution for a specific application should be determined.

Positive_Control: Human dendritic cells. Human lymph nodes and tonsils.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CD11c

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Autre désignation: ITGAX (ITGAX Produits)

Synonymes: anticorps CD11C, anticorps SLEB6, anticorps RGD1561123, anticorps AI449405, anticorps Cd11c, anticorps Cr4, anticorps N418, anticorps integrin subunit alpha X, anticorps integrin alpha X, anticorps ITGAX, anticorps Itgax

Sujet: CD11 antigen-like family member C, Complement component 3 receptor 4 subunit, Integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), Leu M5 alpha subunit, Leukocyte adhesion glycoprotein p150 95 alpha chain, Myeloid membrane antigen alpha subunit, p150/95,CD11c (Dendritic Cell Marker)
Cellular localisation: Cell surface

Poids moléculaire: 145kDa

ID gène: 3687, 248472

UniProt: P20702

Pathways: Système du Complément, Activated T Cell Proliferation, Integrin Complex