ITPR1 anticorps

N° du produit ABIN6943847

Détail du produit anti-ITPR1 anticorps

Antigène: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ITPR1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Human IP3 receptor aa 1770-1900

Clone: 5G10

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store for 1 year at -20°C from date of shipment.

Date de péremption: 12 months

Détails sur ITPR1

Antigène: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Autre désignation: ITPR1 (ITPR1 Produits)

Synonymes: anticorps D6Pas2, anticorps ENSMUSG00000072853, anticorps Gm10429, anticorps IP3R1, anticorps InsP3R, anticorps Ip3r, anticorps Itpr-1, anticorps P400, anticorps Pcp-1, anticorps Pcp1, anticorps opt, anticorps I145TR, anticorps InsP3R1, anticorps INSP3R1, anticorps IP3R, anticorps SCA15, anticorps SCA16, anticorps SCA29, anticorps inositol 1,4,5-trisphosphate receptor type 1, anticorps inositol 1,4,5-trisphosphate receptor 1, anticorps inositol 1,4,5-trisphosphate receptor, type 1, anticorps ITPR1, anticorps Itpr1

Sujet:

Synonyms: Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1, IP3 Receptor.

Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

ID gène: 3708

UniProt: Q14643

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma