Retinoblastoma Binding Protein 8 anticorps (AA 430-480)

N° du produit ABIN6991341

Détail du produit anti-Retinoblastoma Binding Protein 8 anticorps

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Épitope: AA 430-480

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: RBBP8 Antibody is affinity chromatography purified via peptide column.

Immunogène: RBBP8 antibody was raised against a 14 amino acid synthetic peptide near the center of human RBBP8. The immunogen is located within amino acids 430 - 480 of RBBP8.

Isotype: IgG

Information d'application

Indications d'application: RBBP8 antibody can be used for detection of RBBP8 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RBBP8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RBBP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Retinoblastoma Binding Protein 8

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Autre désignation: RBBP8 (RBBP8 Produits)

Synonymes: anticorps COM1, anticorps CTIP, anticorps JWDS, anticorps RIM, anticorps SAE2, anticorps SCKL2, anticorps 9930104E21Rik, anticorps CtIP, anticorps RBBP-8, anticorps RGD1308872, anticorps RBBP8, anticorps DKFZp469K0714, anticorps RB binding protein 8, endonuclease, anticorps retinoblastoma binding protein 8, endonuclease, anticorps retinoblastoma binding protein 8 L homeolog, anticorps retinoblastoma binding protein 8, anticorps RBBP8, anticorps Rbbp8, anticorps rbbp8.L, anticorps rbbp8

Sujet: RBBP8 Antibody: RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway.

ID gène: 5932

NCBI Accession: NP_976037

UniProt: Q99708

Pathways: Cycle Cellulaire, Réparation de l'ADN