NLRP6 anticorps (N-Term)

N° du produit ABIN6991403

Détail du produit anti-NLRP6 anticorps

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Épitope: AA 150-200, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP6 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Purification: NALP6 Antibody is affinity chromatography purified via peptide column.

Immunogène: NALP6 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP6. The immunogen is located within amino acids 150 - 200 of NALP6.

Isotype: IgG

Information d'application

Indications d'application: NALP6 antibody can be used for detection of NALP6 by Western blot at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NALP6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: NALP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NLRP6

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Autre désignation: NALP6 (NLRP6 Produits)

Synonymes: anticorps NLRP6, anticorps NALP6, anticorps AVR, anticorps CLR11.4, anticorps NAVR, anticorps NAVR/AVR, anticorps PAN3, anticorps PYPAF5, anticorps AI504961, anticorps Avr, anticorps Nalp6, anticorps Navr, anticorps Navr/Avr, anticorps Pypaf5, anticorps NLR family pyrin domain containing 6, anticorps NLR family, pyrin domain containing 6, anticorps NLRP6, anticorps Nlrp6

Sujet: NALP6 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-κ,B and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.

ID gène: 171389

NCBI Accession: NP_612202

UniProt: P59044

Pathways: Inflammasome