SARM1 anticorps (N-Term)

N° du produit ABIN6991709

Détail du produit anti-SARM1 anticorps

Antigène: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Épitope: AA 30-80, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SARM1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Specificité: At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. SARM antibody recognize the longest isoform.

Purification: SARM Antibody is affinity chromatography purified via peptide column.

Immunogène: SARM antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SARM. The immunogen is located within amino acids 30 - 80 of SARM.

Isotype: IgG

Information d'application

Indications d'application: SARM antibody can be used for detection of SARM by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SARM Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SARM antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SARM1

Antigène: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Autre désignation: SARM (SARM1 Produits)

Synonymes: anticorps A830091I15Rik, anticorps C78606, anticorps MyD885, anticorps Sarm, anticorps MyD88-5, anticorps SAMD2, anticorps SARM, anticorps sterile alpha and TIR motif containing 1, anticorps sterile alpha and HEAT/Armadillo motif containing 1, anticorps SARM1, anticorps Sarm1, anticorps sarm1

Sujet: SARM Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-κ,B, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interleukin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.

ID gène: 23098

NCBI Accession: NP_055892

UniProt: Q6SZW1

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades