LAMTOR1 anticorps (N-Term)

N° du produit ABIN6991973

Détail du produit anti-LAMTOR1 anticorps

Antigène: LAMTOR1 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAMTOR1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: LAMTOR1 antibody is human, mouse and rat specific. LAMTOR1 antibody is predicted to not cross-react with other LAMTOR family proteins.

Purification: LAMTOR1 antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal LAMTOR1 antibody was raised against a 17 amino acid peptide near the amino terminus of human LAMTOR1 . The immunogen is located within the first 50 amino acids of LAMTOR1.

Isotype: IgG

Information d'application

Indications d'application: LAMTOR1 antibody can be used for detection of LAMTOR1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LAMTOR1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LAMTOR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur LAMTOR1

Antigène: LAMTOR1 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))

Autre désignation: LAMTOR1 (LAMTOR1 Produits)

Synonymes: anticorps C11orf59, anticorps PDRO, anticorps Ragulator1, anticorps p18, anticorps p27RF-Rho, anticorps 2400001E08Rik, anticorps Pdro, anticorps C15H11orf59, anticorps c11orf59, anticorps flj20625, anticorps p27rf-rho, anticorps pdro, anticorps ragulator1, anticorps late endosomal/lysosomal adaptor, MAPK and MTOR activator 1, anticorps late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 S homeolog, anticorps LAMTOR1, anticorps Lamtor1, anticorps lamtor1.S

Sujet: LAMTOR1 is a 161 amino acid membrane protein belonging to the LAMTOR family. It has been identified to interact with and recruit the four Rag GTPases (Rag A-D) to the surface of lysosomes (1). The mTORC1 kinase complex is a critical component in the regulation of cell growth (2). As part of the ragulator complex, LAMTOR1 recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids (3). LAMTOR1 may be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes / lysosomes (4).

Poids moléculaire: Predicted: 18 kDa

Observed: 18 kDa

ID gène: 55004

NCBI Accession: NP_060377

UniProt: Q6IAA8