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FGFR1 anticorps
FGFR1
Reactivité: Humain
IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN7008296
Détail du produit anti-FGFR1 anticorps
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Antigène
Voir toutes FGFR1 Anticorps
FGFR1
(Fibroblast Growth Factor Receptor 1 (FGFR1))
Reactivité
Toutes les réactivités sur FGFR1 Anticorps
Humain
Hôte
Toutes les hôtes sur FGFR1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur FGFR1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers FGFR1 Anticorps
Cet anticorp FGFR1 est non-conjugé
Application
Tous les applications à travers FGFR1 Anticorps.
Immunohistochemistry (IHC), Immunofluorescence (IF)
Attributs du produit
Polyclonal Antibody
Purification
Affinity purification
Immunogène
Recombinant fusion protein of human FGFR1 (NP_075598.2).
Isotype
IgG
Top Product
Discover our top product FGFR1 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
IHC 1:50-1:200 IF 1:50-1:200
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur FGFR1
(cache)
Antigène
FGFR1
(Fibroblast Growth Factor Receptor 1 (FGFR1))
Autre désignation
FGFR1 (FGFR1 Produits )
Synonymes
anticorps FGFR, anticorps fgfr, anticorps X1FGFR, anticorps XFGFR-1, anticorps XFGFRA2, anticorps bfgfr, anticorps cek, anticorps fgfr1, anticorps flg, anticorps flt-2, anticorps flt2, anticorps kal2, anticorps ogd, anticorps xfgfr1, anticorps CG7223, anticorps CT22273, anticorps CT39172, anticorps DFGF-R1, anticorps DFGF-R2, anticorps DFR-1, anticorps DFR1, anticorps DFR1/DFGF-R2, anticorps DPR3, anticorps DTRK(FR1), anticorps Dfr-1, anticorps Dfr1, anticorps DmHD-38, anticorps Dmel\\CG7223, anticorps Dtk1, anticorps EMS2, anticorps FGF-R2, anticorps FGFR2, anticorps FR1, anticorps Fr1, anticorps HD-38, anticorps HTL/FGFR1, anticorps Htl, anticorps Tk1, anticorps dtk1, anticorps i100, anticorps i150, anticorps i79, anticorps j372, anticorps cd331, anticorps fgfbr, anticorps fgfr-1, anticorps hbgfr, anticorps n-sam, anticorps ach, anticorps cd333, anticorps cek2, anticorps fgfr-3, anticorps hsfgfr3ex, anticorps jtk4, anticorps BFGFR, anticorps CD331, anticorps CEK, anticorps FGFBR, anticorps FGFR-1, anticorps FLG, anticorps FLT-2, anticorps FLT2, anticorps HBGFR, anticorps HH2, anticorps KAL2, anticorps N-SAM, anticorps OGD, anticorps bFGF-R-1, anticorps AW208770, anticorps Eask, anticorps Fgfr-1, anticorps Flt-2, anticorps Hspy, anticorps FLG-1, anticorps FGFRI, anticorps x1fgfr, anticorps cb231, anticorps sb:cb231, anticorps fibroblast growth factor receptor, anticorps fibroblast growth factor receptor 1 S homeolog, anticorps basic fibroblast growth factor receptor 1, anticorps heartless, anticorps fibroblast growth factor receptor 1, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog, anticorps Fibroblast growth factor receptor 1, anticorps fibroblast growth factor receptor 1 L homeolog, anticorps fibroblast growth factor receptor 1a, anticorps FGFR, anticorps fgfr, anticorps fgfr1.S, anticorps CpipJ_CPIJ005849, anticorps htl, anticorps fgfr1, anticorps fgfr3.L, anticorps FGFR1, anticorps Fgfr1, anticorps fgfr1.L, anticorps fgfr1a
Sujet
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
ID gène
2260
UniProt
P11362
Pathways
Signalisation RTK , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Sensory Perception of Sound , Stem Cell Maintenance , S100 Proteins
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