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Recombinant H2AFX anticorps (pSer139)

H2AFX Reactivité: Humain WB, ELISA Hôte: Lapin Monoclonal 1F10 unconjugated Recombinant Antibody
N° du produit ABIN7127309
  • Antigène Voir toutes H2AFX Anticorps
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Type d'anticorp
    Recombinant Antibody
    Épitope
    • 40
    • 26
    • 18
    • 11
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer139
    Reactivité
    • 172
    • 91
    • 60
    • 26
    • 26
    • 20
    • 17
    • 12
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 147
    • 25
    • 2
    Lapin
    Clonalité
    • 127
    • 47
    Monoclonal
    Conjugué
    • 108
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp H2AFX est non-conjugé
    Application
    • 132
    • 52
    • 46
    • 39
    • 33
    • 27
    • 22
    • 21
    • 16
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide
    Clone
    1F10
    Isotype
    IgG
    Top Product
    Discover our top product H2AFX Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:3000-1:10000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Autre désignation
    H2AFX (H2AFX Produits)
    Synonymes
    anticorps H2A.X, anticorps H2A/X, anticorps H2AX, anticorps AW228881, anticorps H2ax, anticorps Hist5-2ax, anticorps gammaH2ax, anticorps zgc:56329, anticorps h2a.x, anticorps h2a/x, anticorps h2ax, anticorps RGD1566119, anticorps h2a, anticorps h2afx, anticorps H2A histone family member X, anticorps H2A histone family, member X, anticorps H2A histone family member X L homeolog, anticorps histone cluster 1, H2ah, anticorps histone cluster 2, H2ab S homeolog, anticorps histone H2AX, anticorps H2AFX, anticorps H2afx, anticorps h2afx, anticorps h2afx.L, anticorps HIST1H2AH, anticorps hist2h2ab.S, anticorps LOC100522201, anticorps LOC100720536
    Sujet

    Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

    Aliases: Histone H2AX, H2a/x, Histone H2A.X, H2AFX, H2AX

    UniProt
    P16104
    Pathways
    Telomere Maintenance, Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
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