EIF2AK2 anticorps (pThr446)
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- Antigène Voir toutes EIF2AK2 Anticorps
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
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Épitope
- pThr446
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EIF2AK2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain, Souris
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogène
- Peptide sequence around phosphorylation site of threonine 446 (K-R-T(p)-R-S) derived from Human PKR.
- Isotype
- IgG
- Top Product
- Discover our top product EIF2AK2 Anticorps primaire
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- Indications d'application
- WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
- Autre désignation
- EIF2AK2 (EIF2AK2 Produits)
- Synonymes
- anticorps PKR, anticorps pkr, anticorps EIF2AK2, anticorps DKFZp469K1934, anticorps EIF2AK1, anticorps PRKR, anticorps 2310047A08Rik, anticorps 4732414G15Rik, anticorps AI467567, anticorps AI747578, anticorps Pkr, anticorps Prkr, anticorps Tik, anticorps eukaryotic translation initiation factor 2 alpha kinase 2, anticorps eukaryotic translation initiation factor 2-alpha kinase 2, anticorps EIF2AK2, anticorps eif2ak2, anticorps Eif2ak2
- Sujet
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Background:
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
Abujiang Pataer, et,al. (2002) Cancer Res, 62: 2239.
K. D. Ryman, et,al. (2005) J. Virol, 79: 1487 - 1499.
Susana Guerra, et,al. (2006) J. Biol. Chem, 281: 18734 - 18745.Aliases: Double stranded RNA activated protein kinase antibody, E2AK2_HUMAN antibody, eIF-2A protein kinase 2 antibody, EIF2AK1 antibody, EIF2AK2 antibody, Eukaryotic translation initiation factor 2 alpha kinase 2 antibody, Eukaryotic translation initiation factor 2-alpha kinase 2 antibody, HGNC:9437 antibody, Interferon induced double stranded RNA activated protein kinase antibody, Interferon inducible elF2 alpha kinase antibody, Interferon inducible RNA dependent protein kinase antibody, Interferon-induced, double-stranded RNA-activated protein kinase antibody, Interferon-inducible RNA-dependent protein kinase antibody, MGC126524 antibody, P1/eIF-2A protein kinase antibody, P1/eIF2A protein kinase antibody, p68 kinase antibody, PKR antibody, PPP1R83 antibody, PRKR antibody, Protein kinase interferon inducible double stranded RNA dependent antibody, Protein kinase RNA activated antibody, Protein kinase RNA-activated antibody, Protein phosphatase 1 regulatory subunit 83 antibody, Serine/threonine protein kinase TIK antibody, Tyrosine protein kinase EIF2AK2 antibody
- UniProt
- P19525
- Pathways
- Réparation de l'ADN, ER-Nucleus Signaling, Hepatitis C
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