EPOR anticorps (pTyr368)
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- Antigène Voir toutes EPOR Anticorps
- EPOR (Erythropoietin Receptor (EPOR))
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Épitope
- pTyr368
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EPOR est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogène
- Peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y(p)-L-V) derived from Human Epo-R.
- Isotype
- IgG
- Top Product
- Discover our top product EPOR Anticorps primaire
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anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR Reactivité: Humain WB, ELISA, IP Hôte: Souris Monoclonal 3D10 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 301-450) antibodyEPOR Reactivité: Humain, Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 470-504), (C-Term) antibodyEPOR Reactivité: Humain WB, FACS Hôte: Lapin Polyclonal RB50846 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 45-244) antibodyEPOR Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibodyEPOR Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 3F6 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 274-508) antibodyEPOR Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 320-506) antibodyEPOR Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR Reactivité: Humain, Souris, Rat ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR Reactivité: Humain FACS, cELISA Hôte: Souris Monoclonal VP-2E8 unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB:1:500-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- EPOR (Erythropoietin Receptor (EPOR))
- Autre désignation
- EPOR (EPOR Produits)
- Synonymes
- anticorps EPOR, anticorps epor, anticorps EPO-R, anticorps erythropoietin receptor, anticorps erythropoietin receptor L homeolog, anticorps EPOR, anticorps epor, anticorps Epor, anticorps epor.L
- Sujet
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Background:
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
Funakoshi-Tago M, et al. (2010) J Biol Chem 285, 5296-307
Sulahian R, Cleaver O, Huang LJ (2009) Blood 113, 5287-97
Zhang YL, et al. (2009) Mol Cell 33, 266-74Aliases: EPO R antibody, EPO Receptor antibody, EPO-R antibody, epor antibody, EPOR_HUMAN antibody, Erythropoietin receptor antibody, Erythropoietin receptor precursor antibody, MGC138358 antibody
- UniProt
- P19235
- Pathways
- Signalistation JAK/STAT
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