DCC anticorps

N° du produit ABIN7190434

Détail du produit anti-DCC anticorps

Antigène: DCC (Deleted in Colorectal Carcinoma (DCC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCC est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human DCC

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DCC

Antigène: DCC (Deleted in Colorectal Carcinoma (DCC))

Autre désignation: DCC (DCC Produits)

Synonymes: anticorps CRC18, anticorps CRCR1, anticorps IGDCC1, anticorps MRMV1, anticorps DCC, anticorps zdcc, anticorps C030036D22Rik, anticorps Igdcc1, anticorps xdcc, anticorps XDCCa, anticorps dcca-A, anticorps Dcc, anticorps DCC netrin 1 receptor, anticorps deleted in colorectal carcinoma, anticorps netrin receptor DCC, anticorps DCC, anticorps dcc, anticorps Dcc, anticorps LOC100712666

Sujet:

Background: This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

Aliases: Colorectal cancer related chromosome sequence 18 antibody, Colorectal cancer suppressor antibody, CRC 18 antibody, CRC18 antibody, CRCR 1 antibody, CRCR1 antibody, DCC antibody, DCC_HUMAN antibody, Deleted in colorectal cancer protein antibody, Deleted in colorectal carcinoma antibody, Immunoglobulin superfamily DCC subclass member 1 antibody, Netrin receptor DCC antibody, Tumor suppressor protein DCC antibody

UniProt: P43146

Pathways: Regulation of Cell Size