IL1R2 anticorps (AA 14-343)

N° du produit ABIN7193773

Détail du produit anti-IL1R2 anticorps

Antigène: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Épitope: AA 14-343

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL1R2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human CD121B (AA: extra 14-343) expressed in HEK293-6e cells supernatant.

Clone: 5D7B1

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500 - 1:2000, ICC:1:50 - 1:200, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur IL1R2

Antigène: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Autre désignation: CD121B (IL1R2 Produits)

Synonymes: anticorps CD121b, anticorps CDw121b, anticorps IL-1R-2, anticorps IL-1RT-2, anticorps IL-1RT2, anticorps IL1R2c, anticorps IL1RB, anticorps Il1r-2, anticorps IL-1R2, anticorps interleukin 1 receptor type 2, anticorps interleukin 1 receptor, type II, anticorps interleukin-like, anticorps IL1R2, anticorps Il1r2, anticorps KK34

Sujet:

Description: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.

Aliases: IL1R2,IL1RB, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2

Poids moléculaire: 45.4 kDa

ID gène: 7850

Pathways: Signalisation NF-kappaB