ATF2 anticorps (pThr71)

N° du produit ABIN7265404

Détail du produit anti-ATF2 anticorps

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Épitope: pThr71

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ATF2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Phospho-ATF2-T71 Rabbit mAb

Réactivité croisée: Humain, Souris

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding T71 of human ATF2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATF2

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Autre désignation: ATF2 (ATF2 Produits)

Synonymes: anticorps CRE-BP1, anticorps CREB2, anticorps HB16, anticorps TREB7, anticorps CG12850, anticorps CG3749, anticorps dATF-2, anticorps DmelCG30420, anticorps CG30420, anticorps CHN1, anticorps Atf-2, anticorps CRE-BP, anticorps Creb2, anticorps D130078H02Rik, anticorps D18875, anticorps Tg(Gzma-Klra1)7Wum, anticorps mXBP, anticorps atf2-A, anticorps atf2l, anticorps activating transcription factor 2, anticorps Activating transcription factor-2, anticorps activating transcription factor 2 S homeolog, anticorps ATF2, anticorps Atf-2, anticorps Atf2, anticorps atf2.S, anticorps atf2

Sujet: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014],CRE-BP1, CREB-2, CREB2, HB16, TREB7,B Cell Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Innate Immunity_TLR Signaling,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Protein phosphorylation,Signal Transduction,Toll-like Receptor Signaling Pathway,Transcription Factors,ATF2

Poids moléculaire: 70kDa

ID gène: 1386

UniProt: P15336

Pathways: Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades