HRAS anticorps (AA 101-152) (Alexa Fluor 488)

N° du produit ABIN901260

Détail du produit anti-HRAS anticorps (Alexa Fluor 488)

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Épitope: AA 101-152

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRAS est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Souris, Rat

Homologie: Human,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human H-ras

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HRAS

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Autre désignation: HRAS (HRAS Produits)

Synonymes: anticorps C-BAS/HAS, anticorps C-H-RAS, anticorps C-HA-RAS1, anticorps CTLO, anticorps H-RASIDX, anticorps HAMSV, anticorps HRAS1, anticorps K-RAS, anticorps N-RAS, anticorps RASH1, anticorps hras, anticorps zgc:110250, anticorps HRAS, anticorps H-RAS, anticorps c-H-ras, anticorps H-Ras, anticorps K-Ras, anticorps hras1, anticorps rash1, anticorps ras, anticorps N-Ras, anticorps c-bas/has, anticorps H-ras, anticorps Ha-ras, anticorps Harvey-ras, anticorps Hras-1, anticorps Kras2, anticorps c-Ha-ras, anticorps c-rasHa, anticorps hrasl, anticorps zgc:110734, anticorps HRas proto-oncogene, GTPase, anticorps v-Ha-ras Harvey rat sarcoma viral oncogene homolog a, anticorps neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene, anticorps Harvey rat sarcoma viral oncogene homolog L homeolog, anticorps Harvey rat sarcoma viral oncogene homolog, anticorps Harvey rat sarcoma virus oncogene, anticorps NRAS proto-oncogene, GTPase, anticorps -Ha-ras Harvey rat sarcoma viral oncogene homolog b, anticorps HRAS, anticorps hrasa, anticorps LOC733587, anticorps Hras, anticorps hras.L, anticorps hras, anticorps NRAS, anticorps hrasb

Sujet:

Synonyms: c bas/has, c H ras, c has/bas p21 protein, C K RAS, c K ras2 protein, c Ki ras, c Kirsten ras protein, c ras Ki 2 protein, Cellular c Ki ras2 proto oncogene antibody G1III6 N ras, GTPase HRas, GTPase KRas, GTPase NRas, H Ras 1, H RasIDX, Ha Ras, HRAS 1, HRAS, HRAS1, K Ras 2, K ras, K ras p21 protein, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, Kirsten rat sarcoma 2 viral v Ki ras2 oncogene homolog, KRAS 1, KRAS 2, KRAS, KRAS1, KRAS2, N ras, N ras oncogene, Neuroblastoma RAS viral v ras oncogene homolog, NRAS 1, NRAS, NRAS1, NS3, Oncogene KRAS2, p21ras, PR310 c K ras oncogene antibody RASH 1, RASH1, RASK 2, RASK2, Transforming protein N Ras, Transforming protein p21, v Ha ras Harvey rat sarcoma viral oncogene homolog, v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v Ki ras2 Kirsten rat sarcoma viral oncogene homolog, v ras neuroblastoma RAS viral oncogene homolog, RASH_HUMAN.

Background: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq].

ID gène: 3265

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling