IL1R2 anticorps (AA 301-398) (Alexa Fluor 647)
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- Antigène Voir toutes IL1R2 Anticorps
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
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Épitope
- AA 301-398
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL1R2 est conjugé à/à la Alexa Fluor 647
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human IL-1R II
- Isotype
- IgG
- Top Product
- Discover our top product IL1R2 Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- Autre désignation
- IL-1R2 (IL1R2 Produits)
- Synonymes
- anticorps CD121b, anticorps CDw121b, anticorps IL-1R-2, anticorps IL-1RT-2, anticorps IL-1RT2, anticorps IL1R2c, anticorps IL1RB, anticorps Il1r-2, anticorps IL-1R2, anticorps interleukin 1 receptor type 2, anticorps interleukin 1 receptor, type II, anticorps interleukin-like, anticorps IL1R2, anticorps Il1r2, anticorps KK34
- Sujet
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Synonyms: IL1RB, CD121b, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2, Interleukin-1 receptor type 2, CD121 antigen-like family member B, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, IL1R2
Background: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
- ID gène
- 7850
- UniProt
- P27930
- Pathways
- Signalisation NF-kappaB
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