FGFR1 anticorps (Isoform beta, N-Term, Pro23)

N° du produit ABIN951301

Détail du produit anti-FGFR1 anticorps

Antigène: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Épitope: Isoform beta, N-Term, Pro23

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGFR1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Reacts with the beta isoform of FGFR1. Epitope is undetermined but presumed to be near junction of the common FGFR1 NH2-terminus and NH2-terminus of Ig loop II.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography

Immunogène: Recombinant Human ectodomain of FGFr1-beta expressed in E. coli beginning with Pro23, Antigen containing NH2-terminal Gly-Ser-Pro-Gly-Ile and COOH-terminal Glu-Phe sequences.

Clone: M17A3

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted at -20 °C only.

Détails sur FGFR1

Antigène: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Autre désignation: FGFR1 (FGFR1 Produits)

Synonymes: anticorps FGFR, anticorps fgfr, anticorps X1FGFR, anticorps XFGFR-1, anticorps XFGFRA2, anticorps bfgfr, anticorps cek, anticorps fgfr1, anticorps flg, anticorps flt-2, anticorps flt2, anticorps kal2, anticorps ogd, anticorps xfgfr1, anticorps CG7223, anticorps CT22273, anticorps CT39172, anticorps DFGF-R1, anticorps DFGF-R2, anticorps DFR-1, anticorps DFR1, anticorps DFR1/DFGF-R2, anticorps DPR3, anticorps DTRK(FR1), anticorps Dfr-1, anticorps Dfr1, anticorps DmHD-38, anticorps Dmel\\CG7223, anticorps Dtk1, anticorps EMS2, anticorps FGF-R2, anticorps FGFR2, anticorps FR1, anticorps Fr1, anticorps HD-38, anticorps HTL/FGFR1, anticorps Htl, anticorps Tk1, anticorps dtk1, anticorps i100, anticorps i150, anticorps i79, anticorps j372, anticorps cd331, anticorps fgfbr, anticorps fgfr-1, anticorps hbgfr, anticorps n-sam, anticorps ach, anticorps cd333, anticorps cek2, anticorps fgfr-3, anticorps hsfgfr3ex, anticorps jtk4, anticorps BFGFR, anticorps CD331, anticorps CEK, anticorps FGFBR, anticorps FGFR-1, anticorps FLG, anticorps FLT-2, anticorps FLT2, anticorps HBGFR, anticorps HH2, anticorps KAL2, anticorps N-SAM, anticorps OGD, anticorps bFGF-R-1, anticorps AW208770, anticorps Eask, anticorps Fgfr-1, anticorps Flt-2, anticorps Hspy, anticorps FLG-1, anticorps FGFRI, anticorps x1fgfr, anticorps cb231, anticorps sb:cb231, anticorps fibroblast growth factor receptor, anticorps fibroblast growth factor receptor 1 S homeolog, anticorps basic fibroblast growth factor receptor 1, anticorps heartless, anticorps fibroblast growth factor receptor 1, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog, anticorps Fibroblast growth factor receptor 1, anticorps fibroblast growth factor receptor 1 L homeolog, anticorps fibroblast growth factor receptor 1a, anticorps FGFR, anticorps fgfr, anticorps fgfr1.S, anticorps CpipJ_CPIJ005849, anticorps htl, anticorps fgfr1, anticorps fgfr3.L, anticorps FGFR1, anticorps Fgfr1, anticorps fgfr1.L, anticorps fgfr1a

Sujet: FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family and contains an Ig-like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is widely expressed, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N-cadherin and NCAM.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1

ID gène: 2260

NCBI Accession: NP_001167534

UniProt: P11362

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins