IKK alpha anticorps (AA 500-590)

N° du produit ABIN969054

Cité dans 1 publication. Cet anticorps anti-IKK alpha Monoclonal Souris (Clone 7C10B6) (ABIN969054) détecte spécifiquement IKK alpha dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IKK alpha anticorps (AA 500-590) (ABIN969054)

Antigène: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IKK alpha est non-conjugé

Application: ELISA

Clone: 7C10B6

Détail du produit anti-IKK alpha anticorps

Épitope: AA 500-590

Fonction: CHUK Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of CHUK (aa500-590) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-IKK alpha (ABIN969054)

Prajapati, Verma, Yamamoto, Kwak, Gaynor: "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity." dans: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, (2004) (PubMed).

Détails sur IKK alpha

Antigène: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Autre désignation: CHUK

Sujet: CHUK: conserved helix-loop-helix ubiquitous kinase. This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

ID gène: 1147

UniProt: O15111

Pathways: Signalisation PI3K-Akt, Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins