IKK alpha anticorps

N° du produit ABIN969056

Il existe 1 publication pour ce produit. L’anticorps anti-IKK alpha Monoclonal Souris est utilisé pour la détection de IKK alpha dans des échantillons de Humain. Il a été validé pour WB, ELISA, ICC et FACS.

Aperçu rapide pour IKK alpha anticorps (ABIN969056)

Antigène: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IKK alpha est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 3G12H9

Détail du produit anti-IKK alpha anticorps

Fonction: CHUK Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CHUK expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-IKK alpha (ABIN969056)

Wu, Jan, Tsay, Yu, Huang, Lin, Liu, Chen, Lo, Yu: "Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling." dans: Molecular cancer, Vol. 9, pp. 283, (2010) (PubMed).

Détails sur IKK alpha

Antigène: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Autre désignation: CHUK

Sujet: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Poids moléculaire: 85 kDa

ID gène: 1147

UniProt: O15111

Pathways: Signalisation PI3K-Akt, Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins