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IL-3 Protein (AA 27-166) (His tag)

IL-3 Origine: Rat Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
N° du produit ABIN2018105
  • Antigène Voir toutes IL-3 Protéines
    IL-3 (Interleukin 3 (IL-3))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 27-166
    Origine
    • 23
    • 12
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Source
    • 26
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    CHO Cells
    Purification/Conjugué
    Cette IL-3 protéine est marqué à la His tag.
    Attributs du produit
    ED50 < 8 ng/mL, measured in a cell proliferation assay using NF S-60 cells.
    AA 27-166, expressed with C-terminal 6xHis.
    Pureté
    > 95 % as analyzed by SDS-PAGE.
    niveau d'endotoxine
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL-3 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Stock
    -80 °C
    Stockage commentaire
    Lyophilized recombinant ratInterleukin-3 (IL-3), His remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rat Interleukin-3 (IL-3), His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Date de péremption
    6 months
  • Antigène
    IL-3 (Interleukin 3 (IL-3))
    Autre désignation
    Interleukin-3 (IL-3) (IL-3 Produits)
    Synonymes
    BPA Protein, Csfmu Protein, HCGF Protein, Il-3 Protein, MCGF Protein, PSF Protein, IL-3 Protein, MULTI-CSF Protein, interleukin 3 Protein, interleukin 3 (colony-stimulating factor, multiple) Protein, Il3 Protein, IL3 Protein
    Sujet
    Interleukin-3 (IL-3), also known as MCGF, Multi-CSF, HCGF and P-cell stimulation factor, belongs tothe alpha-helixfamily of hematopoietic cytokines. It is produced by activated T-cells, mast cells and natural killer cells. IL-3 binds to the IL-3 receptor alpha subunit and recruits the signal-transducing common beta chain. IL-3induced signal transduction results in the survival, differentiation and proliferation of a variety of immune cells, such as macrophages, neutrophils, megakaryocytes, mast cells and hematopoietic stem cells. IL-3 often acts synergistically with other cytokines, such as IL-7, EPO, GM-CSF and IL-6, to exert its simulative function.
    Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
    Poids moléculaire
    22-34 kDa, observed by reducing SDS-PAGE.
    UniProt
    P04823
    Pathways
    Signalistation JAK/STAT, Regulation of Carbohydrate Metabolic Process, Autophagy
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