MAPK11 Protein (AA 1-364) (His tag)

N° du produit ABIN666645

Détail du produit

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Type de proteíne: Recombinant

Attributs du protein: AA 1-364

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MAPK11 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: MAPK11, 1-364aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Autre désignation: MAPK11 (MAPK11 Produits)

Synonymes: ATMPK11 Protein, F22L4.10 Protein, F22L4_10 Protein, MAP kinase 11 Protein, zgc:86905 Protein, P38B Protein, P38BETA2 Protein, PRKM11 Protein, SAPK2 Protein, SAPK2B Protein, p38-2 Protein, p38Beta Protein, P38b Protein, Prkm11 Protein, Sapk2 Protein, Sapk2b Protein, p38beta Protein, p38beta2 Protein, p38b Protein, sapk2 Protein, prkm11 Protein, sapk2b Protein, mitogen-activated protein kinase 11 Protein, MAP kinase 11 Protein, mapk11 Protein, LOC9328118 Protein, MPK11 Protein, MAPK11 Protein, Mapk11 Protein, PTRG_02565 Protein

Sujet: MAPK11 (Mitogen-activated protein kinase 11) is a member of the MAP kinase family. This kinase is most closely related to p38 MAP kinases(MAPKs). MAPKs are activated primarily in response to inflammatory cytokines and cellular stress, and inhibitors which target the MAPK14 and MAPK11 have shown potential for the treatment of inflammatory disease. MAPK11 has been shown to interact with HDAC3 and Promyelocytic leukemia protein. This kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Recombinant human MAPK11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Mitogen-activated protein kinase 11, p38-2, P38B, p38Beta, P38BETA2, PRKM11, SAPK2, SAPK2B. NCBI no.: NP_002742

Poids moléculaire: 43.8kDa (387aa), confirmed by MALDI-TOF

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins