TACSTD2 Protein (AA 27-274) (His tag,AVI tag,Biotin)

N° du produit ABIN6731334

Détail du produit

Antigène: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Type de proteíne: Recombinant

Attributs du protein: AA 27-274

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TACSTD2 protéine est marqué à la His tag,AVI tag,Biotin.

Séquence: AA 27-274

Specificité: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Pureté: >90 % as determined by reduced SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Commentaires:

Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Détail du antigène

Antigène: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Autre désignation: TROP-2 (TACSTD2 Produits)

Synonymes: EGP-1 Protein, EGP1 Protein, GA733-1 Protein, GA7331 Protein, GP50 Protein, M1S1 Protein, TROP2 Protein, C80403 Protein, Ly97 Protein, Prp1 Protein, tumor associated calcium signal transducer 2 Protein, tumor-associated calcium signal transducer 2 Protein, TACSTD2 Protein, Tacstd2 Protein

Sujet: TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

Poids moléculaire: 31.6 kDa

NCBI Accession: NP_002344