EGFR Protein (His tag)

N° du produit ABIN6964078

Détail du produit

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EGFR protéine est marqué à la His tag.

Application: ELISA

Fonction: Recombinant human EGFR Protein with C-terminal 6xHis tag

Specificité: EGFR (Leu25-Ser645) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Date de péremption: 12 months

Détail du antigène

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Autre désignation: EGFR (EGFR Produits)

Synonymes: C-erb Protein, CG10079 Protein, D-EGFR Protein, D-Egf Protein, DEGFR Protein, DER Protein, DER flb Protein, DER/EGFR Protein, DER/faint little ball Protein, DER/top Protein, DER/torpedo Protein, DER1 Protein, DEgfr Protein, Degfr Protein, Der Protein, DmHD-33 Protein, Dmel\\CG10079 Protein, EFG-R Protein, EGF-R Protein, EGFR Protein, EGFr Protein, EGfr Protein, EK2-6 Protein, Egf Protein, Egf-r Protein, EgfR Protein, El Protein, Elp Protein, Elp-1 Protein, Elp-B1 Protein, Elp-B1RB1 Protein, HD-33 Protein, TOP Protein, Torpedo/DER Protein, Torpedo/Egfr Protein, c-erbB Protein, d-egf-r Protein, dEGFR Protein, dEGFR1 Protein, dEgfr Protein, der Protein, egfr Protein, flb Protein, l(2)05351 Protein, l(2)09261 Protein, l(2)57DEFa Protein, l(2)57EFa Protein, l(2)57Ea Protein, mor1 Protein, top Protein, top/DER Protein, top/flb Protein, torpedo/Egfr Protein, torpedo/egfr Protein, EGFR12 Protein, EGFR15 Protein, egfr1 Protein, Erbb2 Protein, ERBB Protein, ERBB1 Protein, HER1 Protein, PIG61 Protein, mENA Protein, ErbB-1 Protein, Errp Protein, 9030024J15Rik Protein, AI552599 Protein, Erbb Protein, Errb1 Protein, Wa5 Protein, wa-2 Protein, wa2 Protein, epidermal growth factor receptor Protein, Epidermal growth factor receptor Protein, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) Protein, EGFR Protein, Egfr Protein, egfra Protein, egfr1 Protein, LOC5564544 Protein

Sujet: Synonymes: EGFR,ERBB,ERBB1,HER1,PIG61,mENA
Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Poids moléculaire: predicted molecular mass of 69.4 kDa after removal of the signal peptide.The apparent molecular mass of EGFR-His is 100-130 kDa due to glycosylation.

ID gène: 1956

UniProt: P00533

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins