JAK1 Protein (AA 561-852) (His tag)
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- Antigène Voir toutes JAK1 Protéines
- JAK1 (Janus Kinase 1 (JAK1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 561-852
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Origine
- Humain
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Source
- Cellules d'insectes
- Purification/Conjugué
- Cette JAK1 protéine est marqué à la His tag.
- Attributs du produit
- Human JAK1 Protein, His Tag
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product JAK1 Protéine
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Janus Kinase 1 (JAK1) (AA 850-1154) (Active) protein (GST tag)
JAK1 Origine: Humain Hôte: Insect cells (Sf21) Recombinant SDS, Func Active
Janus Kinase 1 (JAK1) (AA 221-320) protein (GST tag)JAK1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Janus Kinase 1 (JAK1) (AA 1-1154) protein (Strep Tag)Crystallography grade JAK1 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Janus Kinase 1 (JAK1) (AA 1-1153) protein (Strep Tag)Crystallography grade JAK1 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Janus Kinase 1 (JAK1) proteinJAK1 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Janus Kinase 1 (JAK1) protein (Myc-DYKDDDDK Tag)JAK1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 50 mM Tris, 500 mM NaCl, 2 mM TCEP, pH 8.0
- Stock
- -80 °C
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- Antigène
- JAK1 (Janus Kinase 1 (JAK1))
- Autre désignation
- JAK1 (JAK1 Produits)
- Synonymes
- JAK1A Protein, JAK1B Protein, JTK3 Protein, AA960307 Protein, C130039L05Rik Protein, wu:fb93e10 Protein, jak1 Protein, Janus kinase 1 Protein, tyrosine-protein kinase JAK1 Protein, JAK1 Protein, Jak1 Protein, jak1 Protein, LOC100286690 Protein
- Sujet
- JAK1 is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines. It interacts with the common gamma chain (γc) of type I cytokine receptors, to elicit signals from the IL-2 receptor family (e.g. IL-2R, IL-7R, IL-9R and IL-15R), the IL-4 receptor family (e.g. IL-4R and IL-13R), the gp130 receptor family (e.g. IL-6R, IL-11R, LIF-R, OSM-R, cardiotrophin-1 receptor (CT-1R), ciliary neurotrophic factor receptor (CNTF-R), neurotrophin-1 receptor (NNT-1R) and Leptin-R). Jak1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body
- Poids moléculaire
- 35.7 kDa
- Pathways
- Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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