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MASP2 Protein (AA 287-685) (His tag)

MASP2 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
N° du produit ABIN7275293
  • Antigène Voir toutes MASP2 Protéines
    MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 287-685
    Origine
    • 7
    • 3
    • 3
    • 1
    Souris
    Source
    • 6
    • 5
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette MASP2 protéine est marqué à la His tag.
    Fonction
    Mouse MASP2 Protein
    Séquence
    Thr287-Phe685
    Attributs du produit
    Recombinant Mouse MASP2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe685.
    Pureté
    > 95 % as determined by Tris-Bis PAGE
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product MASP2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 50 mM Tris, 200 mM NaCl ( pH 9.0).
    Stock
    -80 °C
    Stockage commentaire
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
    Autre désignation
    MASP2 (MASP2 Produits)
    Synonymes
    MAP19 Protein, MASP-2 Protein, MASP1P1 Protein, sMAP Protein, MAp19 Protein, mannan binding lectin serine peptidase 2 Protein, mannan-binding lectin serine peptidase 2 Protein, MASP2 Protein, Masp2 Protein
    Sujet
    The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.
    Poids moléculaire
    46.6 kDa. Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.
    UniProt
    Q91WP0
    Pathways
    Système du Complément
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