JNK Protein (AA 1-350) (His tag)

N° du produit ABIN7505294

Détail du produit

Antigène: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Type de proteíne: Recombinant

Attributs du protein: AA 1-350

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette JNK protéine est marqué à la His tag.

Séquence: Met1-Glu350

Attributs du produit: A DNA sequence encoding the Human MAPK8 protein (P45983) (Met1-Glu350) was expressed with a C-His,N-His.

Pureté: >95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Autre désignation: JNK1 (MAPK8 Produits)

Synonymes: JNK Protein, JNK-46 Protein, JNK1 Protein, JNK1A2 Protein, JNK21B1/2 Protein, PRKM8 Protein, SAPK1 Protein, SAPK1c Protein, AI849689 Protein, Prkm8 Protein, BSK Protein, BSK/DJNK Protein, Bsk Protein, CG5680 Protein, D-JNK Protein, D-junk Protein, DBSK/JNK Protein, DJNK Protein, DJNK/bsk Protein, Dmel\\CG5680 Protein, JNK/SAPK Protein, Jnk Protein, Junk Protein, SAPKa Protein, c-Jun Protein, dJNK Protein, jnk Protein, T10F20.15 Protein, jnk1 Protein, sapk1 Protein, mapk8 Protein, zgc:112379 Protein, JNKb Protein, mapk8b Protein, mitogen-activated protein kinase 8 Protein, Stress-activated protein kinase jnk-1 Protein, basket Protein, Protein kinase superfamily protein Protein, mitogen-activated protein kinase 8 L homeolog Protein, mitogen-activated protein kinase 8b Protein, mitogen-activated protein kinase 8B-like Protein, MAPK8 Protein, jnk-1 Protein, Mapk8 Protein, bsk Protein, ATMPK8 Protein, mapk8.L Protein, mapk8b Protein, LOC109094263 Protein

Sujet:

Background: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4.

Synonym: JNK,JNK-46,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1,SAPK1c

Poids moléculaire: 38.39 kDa

UniProt: P45983

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins