IL-11 Protéine
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- Antigène Voir toutes IL-11 (IL11) Protéines
- IL-11 (IL11) (Interleukin 11 (IL11))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Séquence
- MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
- Attributs du produit
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Purified recombinant Human IL11 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse T11 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. - Pureté
- > 98 % pure
- niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg) of IL-11.
- Top Product
- Discover our top product IL11 Protéine
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 3 mM Tris, pH 8.0 at the stock concentration of 3 g/mL.
- Buffer
- Supplied as a lyophilized powder.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Antigène
- IL-11 (IL11) (Interleukin 11 (IL11))
- Autre désignation
- IL11 (IL11 Produits)
- Synonymes
- IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
- Sujet
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IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
Alternative Names: AGIF protein, IL-11 protein, IL-11, IL11, IL-11 protein, Interleukin 11 protein, Adipogenesis inhibitory factor protein, IL 11, IL 11 protein - Poids moléculaire
- 19.1 kDa
- Pathways
- Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
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