anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) Anticorps

LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. De plus, nous expédions et LILRB4 Kits (30) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
LILRB4 11006 Q8NHJ6
LILRB4 14728 Q64281
LILRB4    
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Top anti-LILRB4 Anticorps sur anticorps-enligne.fr

Showing 10 out of 80 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IF, ELISA Immunofluorescence analysis of A549 cells, using LILRB4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of CD85K / LILRB4 Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the LILRB4 antibody detected the LILRB4 protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails
Humain Souris PE FACS Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL-3 R alpha/CD123 APC-conjugated Monoclonal Antibody. 100 Tests Connectez-vous pour afficher 8 to 9 Days
$298.32
Détails
Humain Lapin Inconjugué WB LILRB4 Antibody (N-term) (ABIN656231) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the LILRB4 antibody detected the LILRB4 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Souris Fluorescein FACS Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL-3 R alpha/CD123 APC-conjugated Monoclonal Antibody. 100 Tests Connectez-vous pour afficher 8 to 9 Days
$244.08
Détails
Humain Lapin Inconjugué IHC Immunohistochemistry: ILT3/CD85k/LILRB4 Antibody [NBP2-49063] - Staining of human tonsil shows strong cytoplasmic positivity in subset of non-germinal center cells. Immunohistochemistry-Paraffin: ILT3/CD85k/LILRB4 Antibody  - Staining of human tonsil shows strong cytoplasmic positivity in subset of non-germinal center cells. 0.1 mL Connectez-vous pour afficher 34 Days
$494.38
Détails
Souris Lapin Inconjugué ICC, IHC, WB Figure . Western Blot; Sample: Rat Adrenal Gland Tissue. 100 μg Connectez-vous pour afficher 13 to 16 Days
$342.00
Détails
Humain Souris APC FACS Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL-3 R alpha/CD123 PE-conjugated Monoclonal Antibody. 100 Tests Connectez-vous pour afficher 8 to 9 Days
$342.39
Détails
Humain Chèvre Biotin FACS, WB   50 μg Connectez-vous pour afficher 8 to 9 Days
$339.00
Détails
Humain Lapin Inconjugué ELISA, IF   100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails

anti-LILRB4 Anticorps mieux référencés

  1. Human Monoclonal LILRB4 Primary Antibody pour FACS - ABIN4895889 : Zimmer, Luce, Gaignier, Nony, Naveau, Biola-Vidamment, Pallardy, Van Overtvelt, Mascarell, Moingeon: Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae. dans Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal LILRB4 Primary Antibody pour FACS, WB - ABIN4899298 : Waschbisch, Sanderson, Krumbholz, Vlad, Theil, Schwab, Mäurer, Derfuss: Interferon beta and vitamin D synergize to induce immunoregulatory receptors on peripheral blood monocytes of multiple sclerosis patients. dans PLoS ONE 2015 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal LILRB4 Primary Antibody pour FACS - ABIN4895887 : Ulges, Klein, Reuter, Gerlitzki, Hoffmann, Grebe, Staudt, Stergiou, Bohn, Brühl, Muth, Yurugi, Rajalingam, Bellinghausen, Tuettenberg, Hahn, Reißig, Haben, Zipp, Waisman, Probst, Beilhack, Buchou et al.: Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo. ... dans Nature immunology 2015 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal LILRB4 Primary Antibody pour CyTOF, FACS - ABIN4899300 : Gleissner, Zastrow, Klingenberg, Kluger, Konstandin, Celik, Haemmerling, Shankar, Giese, Katus, Dengler: IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells. dans European journal of immunology 2006 (PubMed)

Plus d’anticorps contre LILRB4 partenaires d’interaction

Human Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) interaction partners

  1. Results suggest that ILT3 played an important role in tumor progression in colorectal cancer by possible influence on CD45RO+ T cells in the tumor microenvironment.

  2. These results suggest that tyrosine phosphorylation may be critical in FcgammaRI-dependent endocytosis/phagocytosis that may be regulated by LILRB4 by triggering dephosphorylation of key signalling proteins.

  3. ILT3 may functionally contribute to a regulatory network controlling tumor progression by suppressing the Akt pathway.

  4. The ILT3 PBs/PCs were suggested to be developmentally equivalent based on the simultaneous generation of these populations upon activation of memory B cells in vitro ILT3 expression was found to be induced efficiently by IL-2, while IFN-alpha effectively induced ILT3 PBs/PCs in vitro Utilizing the elevated ILT3 will support opening a new avenue for molecular markers for, pathogenic cells.

  5. this study shows that LILRB4 might have dual inhibitory and activating functions, depending on the position of the functional tyrosine residues in its immunoreceptor tyrosine-based inhibitory motifs and/or the nature of the stimuli

  6. LILRB4 expression is significantly upregulated in human masticatory mucosa during wound healing

  7. Identification of ILT4 as a cellular receptor for CSP C4d

  8. involvement of ILT3 and ILT4 in the modulation of immune responsiveness in multiple sclerosis by both interferon and vitamin D

  9. Cyclosporine up-regulated the expression of ILT3 and ILT4 on natural killer cells, which influenced their cytotoxicity against tumor cells.

  10. ILT3Fc inhibits T cell activation and induces the generation of suppressor T cells targeting multiple inflammatory miRNA pathways.

  11. Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance.

  12. upregulated on antigen-presenting cells in response to Salmonella infection

  13. Data show that LILRB4 is a potent inhibitor of monocyte activation via FcgammaRI.

  14. report that ILT2 receptor, ILT3 receptor, ILT4 receptor, and KIR2DL4 receptor expression is up-regulated by HLA-G histocompatibility antigen in antigen-presenting cells, natural killer cells, and T cells

  15. ILT3 precursor RNA is expressed and retained in nuclei of resting endothelial cells.

  16. Our findings indicate that expression of ILT3 and ILT4 on CLL B cells represents a phenotypic abnormality that may play a role in tolerization of tumor-specific T cells.

  17. The inhibitory effect of serum and membrane ILT3 in a humanized SCID mouse model describes an immune-escape mechanism that could contribute to impaired T cell responses in patients with cancer.

  18. Both membrane and soluble ILT3 are proteins with potent immunosuppressive activity which are of importance for treatment of rejection, autoimmunity and cancer.

  19. describe an immune-escape mechanism mediated by the inhibitory receptor immunoglobulin-like transcript 3 (ILT3) which may be responsible for failure of pancreatic cancer therapy

  20. Progenitor mast cells expressed cell surface inhibitory LILRB4. Mature cord-blood-derived mast cells had detectable mRNA encoding multiple LILRs, none were expressed on the cell surface.

Mouse (Murine) Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) interaction partners

  1. Targeting hepatic LILRB4 to improve its expression or activation represents a promising strategy for the treatment of non alcoholic fatty liver diseases as well as related liver and metabolic diseases

  2. Results suggest that plasma cell development from memory and marginal zone B cells, as well as subsequent antibody production, are suppressed via glycoprotein 49B (gp49B).

  3. LILRB4 can downregulate the development of pathologic allergic inflammation.

  4. receptor attenuates the number of these mature DCs and attendant IL-4-producing lymphocytes in the lymph nodes, and accordingly, the ability of DCs to elicit pathologic Th2 pulmonary inflammation

  5. Inhibition of anaphylactic inflammation by the gp49B1 receptor on mast cells.

  6. Gp49B1 is a unique inhibitory receptor that is induced in multiple lineages of innate and adaptive immune cells during an infection and controls their IFN-gamma, but not cytotoxic responses.

  7. Expression of gp49B was detected on peripheral eosinophils of control mice and on eosinophils from lungs of mice treated with RW, suggesting a role for gp49B on eosinophils in dampening allergic inflammatory responses.

  8. study reports that gp49B, is expressed on dendritic cells and downregulates cellular activity to prevent the excessive activation of T cells in vitro and in vivo

LILRB4 profil antigène

Profil protéine

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LILRB4

  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (LILRB4) anticorps
  • leukocyte immunoglobulin like receptor B4 (LILRB4) anticorps
  • leukocyte immunoglobulin-like receptor, subfamily B, member 4A (Lilrb4a) anticorps
  • CD85K anticorps
  • gp49 anticorps
  • Gp49b anticorps
  • HM18 anticorps
  • ILT-3 anticorps
  • ILT3 anticorps
  • LIR-5 anticorps
  • LIR5 anticorps

Protein level used designations for LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 , CD85 antigen-like family member K , immunoglobulin-like transcript 3 , leukocyte immunoglobulin-like receptor 5 , leukocyte immunoglobulin-like receptor subfamily B member 4 , monocyte inhibitory receptor HM18 , glycoprotein 49 B , mast cell surface glycoprotein Gp49B

GENE ID SPECIES
100587262 Nomascus leucogenys
11006 Homo sapiens
14728 Mus musculus
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