anti-RecQ Protein-Like 5 (RECQL5) Anticorps

The protein encoded by RECQL5 is a helicase that is important for genome stability. De plus, nous expédions RECQL5 Protéines (3) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
RECQL5 9400 O94762
RECQL5 170472  
RECQL5 287834  
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Top anti-RECQL5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 69 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-RECQL5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Transfected 293T 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: RECQL5 Antibody [NBP1-83438] - Staining of human cell line A-431 shows positivity in nucleus & cytoplasm. Immunohistochemistry-Paraffin: RECQL5 Antibody [NBP1-83438] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB RECQL5 Antibody (Center) (ABIN1881739) western blot analysis in human Uterus tissue lysates (35 µg/lane). This demonstrates the RECQL5 antibody detected the RECQL5 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué IP, WB 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Lapin Inconjugué IP, S, WB Western Blot: RECQL5 Antibody  - Detection of Human RECQ5 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-RECQ5 antibody NBP1-40340 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Lapin Inconjugué WB Western blot analysis in human Uterus tissue lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué WB RecQL5 antibody used at 0.25 ug/ml to detect target protein. 50 μg Connectez-vous pour afficher 2 to 3 Days
$473.93
Détails
Humain Souris Inconjugué IF, WB Western Blot analysis of RECQL5 expression in transfected 293T cell line by RECQL5 MaxPab polyclonal antibody.<br><br>Lane 1: RECQL5 transfected lysate(47.85 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to RECQL5 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails

RECQL5 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-RECQL5 Anticorps mieux référencés

  1. Human Polyclonal RECQL5 Primary Antibody pour WB - ABIN1881739 : Schwendener, Raynard, Paliwal, Cheng, Kanagaraj, Shevelev, Stark, Sung, Janscak: Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity. dans The Journal of biological chemistry 2010 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal RECQL5 Primary Antibody pour ICC, IF - ABIN4349789 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. dans Nature methods 2013 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre RECQL5 partenaires d’interaction

Human RecQ Protein-Like 5 (RECQL5) interaction partners

  1. we have shown that increased expression of RECQL5 protein occurs and is likely to contribute to tumourigenesis in UCC and that the pharmacological targeting of the helicase activity of RECQL5 is a strong target for future small molecule inhibitor development.

  2. RECQ5 removes RAD51 filaments stabilizing stalled replication forks at common fragile sites and hence facilitates CFS cleavage by MUS81-EME1.

  3. the open and closed forms of RECQL5 were used together with a quantitative comparison of all current RecQ family structures to construct a mechanistic model for RECQL5 helicase activity

  4. Study characterized the G-quadruplex (GQ) unfolding activity of RECQ5 for different DNA constructs under different salt conditions, showed that RECQ5 is overall a weak GQ destabilizer compared to Bloom and Werner

  5. interaction between RECQ5 and proliferating cell nuclear antigen (PCNA (Montrer PCNA Anticorps)) promotes RAD18 (Montrer RAD18 Anticorps)-dependent PCNA (Montrer PCNA Anticorps) ubiquitination and the helicase activity of RECQ5 promotes the processing of replication intermediates.

  6. RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins

  7. RECQL5 is a critical regulator of genome stability in myeloproliferative neoplasms and demonstrate that replication stress-associated cytotoxicity can be amplified specifically in JAK2V617F mutant cells through RECQL5-targeted synthetic lethality.

  8. Expression of RECQL5 in breast cancer can drive proliferation supporting an oncogenic function for RECQL5 in breast cancer. RECQL5 is a promising biomarker in breast cancer.

  9. RecQ5 prevents transcription associated genome instability by facilitating PIAS1 (Montrer PIAS1 Anticorps)-SRSF1 (Montrer SRSF1 Anticorps) ligase complex sumoylation of DNA topoisomerase 1 (Montrer TOP1 Anticorps).

  10. results suggested RECQL5 as a tumor suppressor in osteosarcoma and may be a potential therapeutic target for osteosarcoma treatment

Mouse (Murine) RecQ Protein-Like 5 (RECQL5) interaction partners

  1. Recql5 protects the liver against LPS (Montrer TLR4 Anticorps)/D-Gal (Montrer GAL Anticorps)-induced injury by suppressing hepatocyte apoptosis and oxidative stress and modulation of CYP450 expression.

  2. Recql5 has a tumor suppressor role in the gastrointestinal tract of Apc (Montrer APC Anticorps)(min) mice.

  3. Recql5-deficient cells exhibit elevated frequencies of spontaneous DNA double-strand breaks and homologous recombination (

  4. Data suggest that Recql5 helps maintain active DNA replication to prevent collapse of replication forks and accumulation of DSBs, preserve genome integrity and prevent cell death after replication stress due to topoisomerase I (Montrer TOP1 Anticorps) poisoning.

RECQL5 profil antigène

Profil protéine

The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RECQL5

  • RecQ like helicase 5 (RECQL5) anticorps
  • RecQ helicase-like 5 (recql5) anticorps
  • ATP-dependent DNA helicase Q5 (LOC100544199) anticorps
  • RecQ protein-like 5 (Recql5) anticorps
  • RecQ like helicase 5 (Recql5) anticorps
  • DKFZp459N0627 anticorps
  • RECQ5 anticorps
  • Recq5b anticorps
  • Recql5b anticorps

Protein level used designations for RECQL5

ATP-dependent DNA helicase Q5 , RecQ protein-like 5 , ATP-dependent DNA helicase Q5-like , DNA helicase, RecQ-like type 5

GENE ID SPECIES
373891 Gallus gallus
454885 Pan troglodytes
566553 Danio rerio
702951 Macaca mulatta
100027279 Monodelphis domestica
100059566 Equus caballus
100173649 Pongo abelii
100216093 Xenopus (Silurana) tropicalis
100225598 Taeniopygia guttata
100397260 Callithrix jacchus
100469169 Ailuropoda melanoleuca
100544199 Meleagris gallopavo
9400 Homo sapiens
512590 Bos taurus
170472 Mus musculus
287834 Rattus norvegicus
483317 Canis lupus familiaris
100626380 Sus scrofa
Fournisseurs de qualité sélectionnés pour anti-RECQL5 (RECQL5) Anticorps
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